Module Catalogues, Xi'an Jiaotong-Liverpool University   
 
Module Code: CHE314
Module Title: Introduction to Separation Sciences
Module Level: Level 3
Module Credits: 2.50
Academic Year: 2017/18
Semester: SEM2
Originating Department: Chemistry
Pre-requisites: N/A
   
Aims
This course covers the theory and application of common separation techniques in use in chemistry. The main focus is however, on chromatographic techniques. Detail theoretical background and instrumentation for HPLC and GC will be given.
Learning outcomes 
A Explain the terminology used in separation sciences

B Describe the general methods used for separation of mixtures and select the most appropriate one in industry and research settings

C Discuss the principles governing the separation of molecules and ions in chromatography

D Explain plate number and separation power of column

E Discuss the key configuration of HPLC and GC

F Critically discuss the principle of electrophoresis

G Discuss the application of these separation techniques in industries and research settings

Method of teaching and learning 
Lectures, tutorial and course works
Syllabus 
1. Methods for the Separation of mixtures

i. solvent-solvent extraction

ii. distillation

iii. chromatography

iv. centrifugation

v. electrophoresis

2. Solvents

i. polarity, viscosity, miscibility, UV cutoff, solvent strength, mixing solvents

3. Sample preparation and precision of measurement

i. cleaning of samples

ii. errors in measurements

4. Introduction to chromatography

i. general description

ii. fundamental principles and equations describing separation

iii. zone broadening

iv. column efficiency

5. General performance characteristics of chromatography

i. linearity

ii. sensitivity

iii. optimization of column performance

iv. quantification

6. Derivatization in chromatographic analysis

i. modification of column materials

7. Column chromatography, Thin layer , Size exclusion, Chiral chromatograpphy

8. HPLC

i. Introduction

ii. Instrumentation: Pumps, injector, mobile phase handling, detector

iii. Normal phase, reverse phase

iv. Ion chromatography

9. Gas chromatography

i. Introduction

ii. Mobile and stationery phases

iii. Columns

iv. Detection

10. Introduction to Electrophoresis


Delivery Hours  
Lectures Seminars Tutorials Lab/Prcaticals Fieldwork / Placement Other(Private study) Total
Hours/Semester 13    7      55  75 

Assessment

Sequence Method % of Final Mark
1 Course Work Assessment 20.00
2 Exam 80.00

Module Catalogue generated from SITS CUT-OFF: 10/22/2017 9:25:59 PM